Detailed research into fish larvae
DanioScope
If you are interested in researching physiological and behavioral parameters in (zebra)fish larvae and embryos, then DanioScope is the tool you need.
Standardized Increase reproducibility with calibrated measurements
Flexible Can handle slightly moving animals by combining measures
Time Saving Acquire data in batches from multiple videos
How does
DanioScope work?
Record
First you record your models under a microscope fitted with a camera. This video is uploaded to DanioScope and analysis can begin. DanioScope supports videos over 60fps and handles a wide range of video formats.
Choose parameters
DanioScope allows you to measure various behavioral and physiological parameters in fish larvae and embryos. This not only allows you to measure behaviors like activity and tail coiling, but also blood flow and heart rate.
Analyze
The software allows you to fine tune results by redefining thresholds. Furthermore, organize your data through flexible selection, grouping and displaying of data. You can easily export your data if you need more in-depth statistics.
Get DanioScope for your lab
Increase the throughput of your research and save time in preparing, acquiring and analyzing your zebrafish larvae and embryo data behavioral and physiological data with DanioScope.
DanioScope perpetual license
Access to all functionality
Measure behavior and physiological parameters
Easy to use & varied applications
Build your complete solution
Hardware
DanioScope works with standard microscopes and cameras. We can help you choose the right setup for your specific application.
NoldusCare
Add an additional year of NoldusCare to keep your software performing at its best. Includes the latest features, ongoing technical support, and access to the Noldus Academy.
Remote training
Ensure a strong start with our remote training sessions. Led by experienced Noldus trainers, these sessions help you quickly become familiar with DanioScope.
Hardware Options
DanioScope Hardware Setup
Microscope, camera, and well plate holder for zebrafish larvae analysis.
NoldusCare Extensions
NoldusCare DanioScope
1 additional year of NoldusCare for DanioScope. Includes updates, support, and Noldus Academy access.
Training Packages
DanioScope Training (Remote)
Remote training session covering DanioScope setup, data acquisition, and analysis workflows.
Applications of DanioScope
Behavioral and physiological parameters to measure
DanioScope is a flexible tool that can be used for many research applications. From toxicology to drug development.
Zebrafish activity
Early embryo movements such as tail flicks, coiling, and convulsive behavior are sensitive readouts for toxicology and pharmacology. DanioScope measures activity non-invasively from video and reports burst activity, inactivity, duration, and movement counts.
Blood/gut flow
Flow measurements add insight if heart rate alone can't give the full picture. DanioScope quantifies blood vessel or gut flow from standard video by analyzing frame-to-frame pixel changes within a selected region, and reports flow as an activity percentage.
Cardiology
Zebrafish are a strong model for cardiac development and function. DanioScope provides fast, video-based heart rate and inter-beat interval assessment: select the heart region once, and the software automatically outputs beats per second and beats per minute.
Morphology
Track growth and malformations over time using images or video snapshots. With simple drawing and calibration tools, DanioScope automatically measures lengths and areas such as tail length, eye size, and pericardial area, or any custom metric you define.
More about DanioScope
Learn more about early life zebrafish research
Parameters in depth
DanioScope explained in 2.5 min
Want to know what parameters DanioScope can measure and how it does this? Watch this short video to learn more about the ins and outs of morphological and behavioral analysis in embryos and larvae.
Novel application of DanioScope
Breathing frequency measurements
Researchers from the University of Heidelberg used DanioScope in a novel way to objectively measure breathing in zebrafish embryos and larvae. You can read all about their methods in this blog.
Frequently asked questions
about DanioScope
Yes, you can measure many of the parameters like blood flow or heart rate separately for multiple animals in the same video file. Just draw and label the boxes around the correct animal.
Yes, you can use DanioScope for other fish species. However, parameters that require organs or vessels to be visible can only be done in transparent animals.
DanioScope can handle a wide variety of cameras and types of video formats. We recommend using a higher sampling rate (60fps) to record the number of frames needed for a high-quality analysis.
Want more info?
Book a demo!
Does this solution sound interesting to you? But do you want more info before making a final decision? Feel free to book a demo with us! We're happy to help you make a choice that fits your needs.