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All I need to know about PhenoTyper

Want to learn more about PhenoTyper? We have a great variety of materials for you to read.

  • Extensive ebooks
  • Interesting white papers
  • Enlightening videos

These materials will help you better understand the full capabilities of the PhenoTyper.

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PhenoTyper videos

Studying optogenetics in the PhenoTyper

Optogenetics is a valuable tool in neurobehavioral research, and equipment can easily be integrated in the PhenoTyper home cage. Control of the stimulation can be programmed via EthoVision XT, based on animal behavior or timing.

Customer succes story University of Toronto

Dr. Thomas Prévôt from the University of Toronto uses the PhenoTyper to study anxiety in order to transform mental health care.

University of Toronto, Canada
EthoVision XT homecage testing

EthoVision XT video tracking automates a whole range of tests, such those performed in the home cage environment (e.g. PhenoTyper) of rats or mice.

PhenoTyper webinar

Phenotyping your rodents: Mapping short- and long-term studies

In this talk, we investigate how animal research can be extended in to long-term observations, following the path human research has entered for some time already which resulted in great new insights.

Reading materials

In vivo calcium imaging

The ability to acquire in vivo neural activity data simultaneously with behavioral data is vital to truly understanding the brain in action. The PhenoTyper has been used to perform calcium imaging for many years, and this has been made even easier with the new modular top unit.

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PhenoTyper 2 all-in-one leaflet

PhenoTyper is a versatile and adaptable system. The many options and verified applications make the PhenoTyper the ideal system for your lab. In this leaflet we go over all the ins and outs of the PhenoTyper and its new top unit.

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Mice avoidance learning

G. Maroteaux et al. used the PhenoTyper system to study avoidance behavior in mice. They trained mice to prefer one of two shelter entrances and applied a light as an aversive stimulus. This method effectively provides unbiased cognitive and behavioral analysis. Download this case study to explore their innovative approach.

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Free e-book

Basic behavioral neuroscience in rodents

Want some more literature on the basic (behavioral) neuroscience in rodents? Download our free e-book. In this guide we explain why and how we investigate specific types of behaviors. Our goal is to help you advance your research by providing high quality products and accurate information at a high level.

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Features blog posts

Calcium imaging and measuring behavior

What is calcium imaging, and how can you this technique to get a better understanding of complex rodent behavior? Read more about the basic principles and benefits of calcium imaging

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The many uses of PhenoTyper

With its new top unit, the PhenoTyper is even more versatile than before. Follow in the footsteps of those who have already added the PhenoTyper to their lab and learn all about its varied applications.

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Mice in the spotlight: why you should perform your tests in a home cage

Mouse models are essential for neuroscience research. Many tests are susceptible to bias. Home cage testing provides a number of solutions.

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Relevant publications

Here is an overview of some recent publications with PhenoTyper. If you feel like your publication should be on this list, send us an e-mail at: [email protected].
Garrick, J.M.; Cole, T.B.; Dao, K.; Phillips, A.; Costa, L.G. Perinatal Diesel Exhaust Exposure Causes Persistent Changes in the Brains of Aged Mice: An Assessment of Behavioral and Biochemical Endpoints Related to Neurodegenerative Disease. Environ. Toxicol. 2023.

Tseitlin, L.; Richmond-Hacham, B.; Vita, A.; Schreiber, S.; Pick, C.G.; Bikovski, L. Measuring Anxiety-like Behavior in a Mouse Model of mTBI: Assessment in Standard and Home Cage Assays. Front. Behav. Neurosci. 2023, 17.
Clifford, K.P.; Miles, A.E.; Prevot, T.D.; Misquitta, K.A.; Ellegood, J.; Lerch, J.P.; Sibille, E.; Nikolova, Y.S.; Banasr, M. Brain Structure and Working Memory Adaptations Associated with Maturation and Aging in Mice. Front. Aging Neurosci. 2023, 15, 1195748,
Stamatakis, A.M.; Schachter, M.J.; Gulati, S.; Zitelli, K.T.; Malanowski, S.; Tajik, A.; Fritz, C.; Trulson, M.; Otte, S.L. Simultaneous Optogenetics and Cellular Resolution Calcium Imaging during Active Behavior Using a Miniaturized Microscope. Front. Neurosci. 2018, 496.
Nicol, M.; Lahaye, E.; El Mehdi, M.; do Rego, J.-L.; do Rego, J.-C.; Fetissov, S.O. Lactobacillus Salivarius and Lactobacillus Gasseri Supplementation Reduces Stress-Induced Sugar Craving in Mice. Eur. Eat. Disord. Rev. 2023, doi:10.1002/erv.3004.
Hatter, J.A.; Scott, M.M. Selective Ablation of VIP Interneurons in the Rodent Prefrontal Cortex Results in Increased Impulsivity. PLOS ONE 2023, 18, e0286209, doi:10.1371/journal.pone.0286209.
Lange, M.E.; Clarke, S.T.; Boras, V.F.; Brown, C.L.J.; Zhang, G.; Laing, C.R.; Uwiera, R.R.E.; Montina, T.; Kalmokoff, M.L.; Taboada, E.N.; et al. Commensal Escherichia Coli Strains of Bovine Origin Competitively Mitigated Escherichia Coli O157:H7 in a Gnotobiotic Murine Intestinal Colonization Model with or without Physiological Stress. Animals 2023, 13, 2577, doi:10.3390/ani13162577.

Faisal, M.; Aid, J.; Nodirov, B.; Lee, B.; Hickey, M.A. Preclinical Trials in Alzheimer’s Disease: Sample Size and Effect Size for Behavioural and Neuropathological Outcomes in 5xFAD Mice. PLOS ONE 2023, 18, e0281003, doi:10.1371/journal.pone.0281003.
Khan, K.M.; Balasubramanian, N.; Gaudencio, G.; Wang, R.; Selvakumar, G.P.; Kolling, L.; Pierson, S.; Tadinada, S.M.; Abel, T.; Hefti, M.; et al. Human Tau-Overexpressing Mice Recapitulate Brainstem Involvement and Neuropsychiatric Features of Early Alzheimer’s Disease. Acta Neuropathol. Commun. 2023, 11, 57, doi:10.1186/s40478-023-01546-5.

Wang, R.; Khan, K.M.; Balasubramanian, N.; James, T.; Pushpavathi, S.G.; Kim, D.; Pierson, S.; Wu, Q.; Niciu, M.J.; Hefti, M.M.; et al. Alcohol Inhibits Sociability via Serotonin Inputs to the Nucleus Accumbens 2023, 2023.05.29.542761.
de Wouters d’Oplinter, A.; Verce, M.; Huwart, S.J.P.; Lessard-Lord, J.; Depommier, C.; Van Hul, M.; Desjardins, Y.; Cani, P.D.; Everard, A. Obese-Associated Gut Microbes and Derived Phenolic Metabolite as Mediators of Excessive Motivation for Food Reward. Microbiome 2023, 11, 94, doi:10.1186/s40168-023-01526-w.
Morrone, C.D.; Tsang, A.A.; Giorshev, S.M.; Craig, E.E.; Yu, W.H. Concurrent Behavioral and Electrophysiological Longitudinal Recordings for in Vivo Assessment of Aging. Front. Aging Neurosci. 2023, 14. doi: 10.3389/fnagi.2022.952101