Alzheimer’s and Parkinson’s Blog Posts

Neurodegenerative diseases such as Alzheimer's and Parkinson's are often characterized by changes in cognition, locomotion, and even anxiety. Measuring these outputs in animal (disease) models is crucial for understanding the underlying mechanisms of these diseases, for applications in humans.

Parkinson's disease research - Relevant measures in pre-clinical studies
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Parkinson's disease research - Relevant measures in pre-clinical studies

Parkinson’s disease: the neurodegenerative disorder that affects mobility in a life-changing way. Learn more about relevant measures in pre-clinical studies.

CatWalk XT ErasmusLadder locomotion neuroscience Parkinson's disease
Alzheimer's research - From prevention research to natural treatment
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Alzheimer's research - From prevention research to natural treatment

Experts estimate that by 2050, 100 million people will have Alzheimer’s disease (AD), which is a shockingly large number. Learn more about the research that has been done in order to find a cure.

Alzheimer's disease EthoVision XT Morris water maze video recording
Using gait analysis to analyze Parkinson’s in rat model
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Using gait analysis to analyze Parkinson’s in rat model

Contrary to common methods, gait analysis can detect clinically relevant symptoms early on, researchers say.

CatWalk XT gait gait analysis Parkinson's disease
Alzheimer research and the Morris water maze task
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Alzheimer research and the Morris water maze task

First developed in 1981 by Richard Morris, the Morris water maze task is still one of the most popular tests for memory and learning in rodents.

EthoVision XT Morris water maze video tracking
Putative neurorestorative drug for Parkinson’s disease tested in zebrafish
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Putative neurorestorative drug for Parkinson’s disease tested in zebrafish

About zebrafish and their important role in finding a cure for Parkinson’s disease.

DanioVision EthoVision XT Parkinson's disease video tracking zebrafish
Spatial and odor memory impaired mice – new model for Alzheimer’s
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Spatial and odor memory impaired mice – new model for Alzheimer’s

Plaques and tangles… those of you even remotely familiar with Alzheimer’s disease (AD) will immediately recognize these hallmarks. But they are linked to familial AD, while sporadic AD is far more common.

EthoVision XT learning and memory mice olfaction video tracking
Dementia symptoms following surgery
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Dementia symptoms following surgery

This week we have a guest post by Iris Hovens. She has done some really interesting research into the consequences of surgery in terms of reduced memory and concentration problems.

dementia EthoVision XT learning and memory novel object test open field video tracking
How to study ataxia
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

How to study ataxia

Ataxia is a common problem in Parkinson’s disease (PD), and many early onset Alzheimer’s disease patients (AD) also deal with it. Now there is a non-invasive test for mouse models.

Alzheimer's disease cerebellum ErasmusLadder gait locomotion motor learning
Alzheimer's: prevent instead of cure?
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Alzheimer's: prevent instead of cure?

Alzheimer’s disease (AD) is a huge public health issue as it affects a large part of the aging population. Neuropathology is studied primarily in the end stages of the disease. What about prevention?

Alzheimer's disease ErasmusLadder gait locomotion motor learning
10 behavioral studies on Alzheimer’s and Parkinson’s
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

10 behavioral studies on Alzheimer’s and Parkinson’s

This blog post features 10 interesting studies that use innovative techniques to study models of AD and PD and important underlying neuronal mechanisms.

Alzheimer's disease CatWalk XT DanioVision ErasmusLadder EthoVision XT gait
How Ginkgo biloba helps treat Alzheimer’s
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

How Ginkgo biloba helps treat Alzheimer’s

Xu Liu and colleagues recently investigated the effects of Ginkgo biloba extract on a mouse model for Alzheimer’s disease (AD).

Alzheimer's disease EthoVision XT learning and memory video tracking
Side effects of L-DOPA investigated in parkinsonian rats
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animal Behavior Research
folder Alzheimer’s and Parkinson’s

Side effects of L-DOPA investigated in parkinsonian rats

These studies specifically investigate the long-term effects of L-DOPA or levopoda, a common clinical treatment for Parkinson's disease, with which many patients struggle.

behavior recognition EthoVision XT Parkinson's disease PhenoTyper video tracking

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