Blog Posts Tagged: gait

Testing motor coordination in a mouse model with muscular dystrophy

Muscular Dystrophy is a broad group of diseases recognized by the loss of muscle mass and strenght. Researchers tried to discover if gene therapy strategies can help with reducing symptoms.

Gait analysis at the PSDL using CatWalk

Our lab studies the Neuronal Ceroid Lipofuscinoses (NCLs) or Batten disease, which are a group of progressive and genetically inherited neurodegenerative diseases that affect children and young adults.

Using gait analysis to analyze Parkinson’s in rat model

Contrary to common methods, gait analysis can detect clinically relevant symptoms early on, researchers say.

Gait recovery and other effects: treatment of cervical myelopathy

At the Dr. Michael Fehlings' lab, they are on a quest to find out what exactly causes the lower success rate of delayed surgery in cervical myelopathy.

Autistic mice have motor learning difficulties specific to the cerebellum

Autism is often associated with social behavior deficits and repetitive behaviors. However, motor abnormalities are also a part of the behavioral spectrum. Recent studies have implicated the cerebellum.

How to let rats run perfectly

Letting animals walk freely in gait research. At Noldus, we strongly believe this is the way to go, so that is how our CatWalk XT system works.

Behavioral effects of optogenetically induced myelination in mice

Myelination, the ‘ensheathment’ of neurons, is essential to the functioning of the central and peripheral nervous systems. So it is not surprising that problems with myelination can lead to a number of crippling diseases.

How to study ataxia

Ataxia is a common problem in Parkinson’s disease (PD), and many early onset Alzheimer’s disease patients (AD) also deal with it. Now there is a non-invasive test for mouse models.

Alzheimer's: prevent instead of cure?

Alzheimer’s disease (AD) is a huge public health issue as it affects a large part of the aging population. Neuropathology is studied primarily in the end stages of the disease. What about prevention?

Gait research: let your animals walk freely

Researchers use different ways to analyze gait in animals. In what instances would a study benefit from a system that is based on voluntary walking?

10 behavioral studies on Alzheimer’s and Parkinson’s

This blog post features 10 interesting studies that use innovative techniques to study models of AD and PD and important underlying neuronal mechanisms.

Parkinson’s & gait impairment: comparing rats and humans

Gait impairment is one of the most prominent symptoms of Parkinson's disease. For good research you need good models and good tests.